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基于脾主运化理论探讨胃癌前病变的中医治疗策略 被引量:10

Exploration of TCM Treatment Strategies for Gastric Precancerous Lesions based on the Theory of Spleen Governing Transportation and Transformation
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摘要 脾主运化是人体"后天之本"的功能物质基础,与机体消化系统的关系密切。胃癌发病病因多由脾失运化、湿浊痰瘀损伤胃络、聚而成毒。故脾主运化功能失司、气机失调是胃癌前病变(PLGC)的重要病机,湿、痰、瘀是PLGC重要病理因素,而脾虚则贯穿PLGC发病的全过程。临床辨治重视健脾理气法的运用,从"脾主运化"角度论治PLGC,对胃癌的防治有重要意义。 The spleen governs transportation and chemistry is the functional material basis of the human body’s “acquired foundation”,and is closely related to the body’s digestive system.The etiology of gastric cancer is mostly caused by the loss of transport of the spleen,dampness,phlegm and blood stasis,damage to the stomach collaterals,and accumulation of poison.Therefore,the dysfunction of the spleen governing transportation and transformation and the imbalance of Qi are important pathogenesis of gastric precancerous lesions (PLGC).Dampness,phlegm,and blood stasis are important pathological factors of PLGC,and spleen deficiency runs through the whole process of PLGC.Clinical differentiation and treatment attaches great importance to the application of the method of strengthening the spleen and regulating qi,and treating PLGC from the perspective of “spleen governing movement and transformation” is of great significance for the prevention and treatment of gastric cancer.
作者 陈祥华 林平 蔡华珠 李思汉 何友成 陈军帅 黄铭涵 CHEN Xianghua;LIN Ping;CAI Huazhu;LI Sihan;HE Youcheng;CHEN Junshuai;HUANG Minghan(The Second People’s Hospital Affiliated of Fujian University of Traditional Chinese Medicine,Fuzhou Fuzhou 350003,China;Fujian University of Traditional Chinese Medicine,Fuzhou Fujian 350122,China;Guangzhou University of Traditional Chinese Medicine,Guangdong Guangzhou 510006,China)
出处 《中医药临床杂志》 2021年第9期1643-1646,共4页 Clinical Journal of Traditional Chinese Medicine
基金 福建省自然科学基金(2020J01253) 福建省医学创新课题(2018-CX-47) 福建省卫健委中青年骨干人才培养项目(2019-ZQN-79) 福建中医药大学中医脾胃学科开放课题(X2019014-学科) 福建中医药大学“中医脾胃优势特色学科”建设项目(X2019017-学科)。
关键词 胃癌前病变 脾主运化 脾虚气滞 健脾理气 Gastric precancerous lesions Spleen governs transportation and transformation Spleen deficiency and Qi stagnation Invigorating spleen and regulating Qi
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