肝癌肝移植术后预防复发的全程管理探讨

Discussion on the whole course management of preventing recurrence of liver cancer after liver transplantation

肝移植是治疗肝细胞癌(hepatocellular carcinoma,HCC)的重要措施之一,尤其是对于合并终末期肝病的患者。但移植术后的肿瘤复发,严重制约了患者的长期生存。因此,如何预防移植术后HCC复发是提高HCC肝移植远期疗效的关键。本文从围手术期的治疗全流程管理的角度,就预防HCC肝移植患者术后复发展开阐述,并从手术、用药等多维度综述相关临床进展。

Liver transplantation is one of the important measures for the treatment of hepatocellular carcinoma,especially for patients with end-stage liver disease.However,tumor recurrence after transplantation severely restricts the patient's long-term survival.Therefore,how to prevent the recurrence of liver cancer after transplantation is the key to improve the long-term efficacy of liver transplantation for liver cancer.This article discusses the prevention of postoperative recurrence of liver cancer patients after liver transplantation from the perspective of perioperative management of the entire treatment process,and reviews relevant clinical progress from multiple dimensions such as surgery and medication.