五联疗法治疗胸腰椎压缩性骨折的疗效分析

Analysis on the therapeutic efficacy of quintuple therapy in the treatment of thoracolumbar compression fracture

目的探讨五联疗法治疗胸腰椎压缩性骨折的疗效。方法将2019年1月至2020年1月我院收治的95例胸腰椎压缩性骨折患者随机分组,对照组45例行常规西医治疗,观察组50例使用五联疗法,对比疗效、椎体前缘高度及Cobb角、骨密度及VAS疼痛评分、生活质量。结果观察组治疗有效率为92.00%,明显高于对照组的73.33%(P<0.05);观察组治疗后3个月、6个月的椎体前缘高度为(20.19±0.42)mm、(20.11±0.48)mm,高于对照组的(16.21±0.47)mm、(15.54±0.42)mm(P<0.05),两组治疗后3个月、6个月的观察组Cobb角(8.72±1.39)°、(9.16±1.43)°与对照组(9.13±1.56)°、(9.29±1.47)°相比,差异无统计学意义(P>0.05);观察组治疗3个月、6个月后的骨密度为(-2.11±0.64)SD、(-1.03±0.25)SD高于对照组的(-2.78±0.75)SD、(-1.89±0.38)SD,观察组治疗后3个月、6个月VAS疼痛评分为(1.29±0.32)分、(0.50±0.15)分,明显低于对照组的(2.43±0.57)分、(1.92±0.39)分(P<0.05);观察组治疗后躯体功能(60.73±8.82)分、情绪功能(72.81±6.36)分、社会功能(71.54±5.35)分、角色功能(78.09±6.23)分高于对照组的(55.68±8.19)分、(62.39±7.04)分、(65.84±6.48)分、(71.39±7.18)分(P<0.05)。结论五联疗法治疗胸腰椎压缩性骨折疗效显著,可恢复椎体高度及弧度,提高骨密度,减轻疼痛,提升生活质量。

Objective To investigate the therapeutic efficacy of quintuple therapy in the treatment of thoracolumbar compression fracture.Methods A total of 95 patients with thoracolumbar compression fracture from January 2019 to January 2020 were randomly divided into the control group(n=45)and the observation group(n=50).The control group was treated with conventional western medicine,while the observation group was treated with quintuple therapy.The therapeutic efficacy,anterior height of vertebral body,Cobb angle,bone mineral density,VAS pain score and quality of life were compared.Results The efficacy rate of the observation group was 92.00%,significantly higher than 73.33%of the control group(P<0.05).The anterior heights of vertebral body in the observation group after 3 and 6 months of treatment were(20.19±0.42)mm and(20.11±0.48)mm,higher than(16.21±0.47)mm and(15.54±0.42)mm in the control group,respectively(P<0.05).Cobb angles of the two groups after 3 and 6 months after treatment were(8.72±1.39)°vs(9.16±1.43)°and(9.13±1.56)°vs.(9.29±1.47)°,with no statistically significant difference(P>0.05).The bone mineral density after 3 months and 6 months of treatment were(-2.11±0.64)SD and(-1.03±0.45)SD in the observation group,higher than(-2.78±0.75)SD and(-1.89±0.38)SD in the control group.The VAS pain scores were(1.29±0.32)points and(0.50±0.15)points,significantly lower than(2.43±0.57)points and(1.92±0.39)points(P<0.05).After treatment,the score of physical function in the observation group was(60.73±8.82)points,emotional function was(72.81±6.36)points,social function was(71.54±5.35)points and role function was(78.09±6.23)points,higher than(55.68±8.19)points,(62.39±7.04)points,(65.84±6.48)points and(71.39±7.18)points in the control group(P<0.05).Conclusion Quintuple therapy is effective in the treatment of thoracolumbar compression fracture,which can restore the height and radian of vertebral body,increase bone mineral density,relieve pain and improve the quality of life.