针对性治疗应用于妊娠期糖尿病合并胎膜早破治疗中的效果观察

Effects of targeted treatment on gestational diabetes mellitus complicated with premature rupture of membranes

目的探讨针对性治疗应用于妊娠期糖尿病合并胎膜早破治疗中的效果观察。方法选取2019年1-12月因妊娠期糖尿病合并胎膜早破来河南省某医院接受治疗的68例患者为研究对象,采用随机数字表法将患者分为研究组与对照组。对照组患者采用宫缩抑制剂治疗。研究组患者采取针对性治疗措施。分娩后,比较2组患者空腹及餐后2 h血糖水平。比较2组患者产后大出血发生情况。比较2组新生儿不良结局及2组新生儿Apgar评分。结果研究组患者空腹及餐后2 h血糖水平均低于对照组,差异均有统计学意义(P<0.05)。研究组患者中发生产后大出血2例,占比5.9%;对照组患者中发生产后大出血3例,占比8.8%。2组患者大出血发生率比较,差异无统计学意义(P>0.05)。研究组新生儿不良结局发生率为2.9%,低于对照组的14.7%,差异有统计学意义(P<0.05)。研究组新生儿Apgar评分为(8.3±0.5)分,高于对照组的(4.0±0.4)分,差异有统计学意义(P<0.05)。结论对妊娠期糖尿病患者进行针对性治疗,并在胎膜早破时进行有效应对,能够减少新生儿不良结局的发生,改善母婴预后,值得临床推广应用。

Objective To explore the effect of targeted treatment on gestational diabetes mellitus complicated with premature rupture of membranes.Methods A total of 68 patients with gestational diabetes mellitus complicated with premature rupture of membranes in a hospital in Henan Province from January to December 2019 were selected as the study subjects.The patients were randomly divided into the study group and the control group.Patients in the control group were treated with uterine contraction inhibitors.The patients in the study group were given targeted treatment.After delivery,the fasting and 2-hour postprandial blood glucose levels were compared between the two groups.The incidence of postpartum hemorrhage was compared between the two groups.The adverse outcome and Apgar score of newborns in the two groups were compared.Results The fasting and 2-hour postprandial blood glucose levels in the study group were significantly lower than those in the control group,and the difference was statistically significant(P<0.05).There were 2 cases of postpartum hemorrhage in the study group,accounting for 5.9%,and 3 cases of postpartum hemorrhage in the control group,accounting for 8.8%.There was no significant difference in the incidence of massive hemorrhage between the two groups(P>0.05).The incidence of adverse outcome among newborns in the study group was 2.9%,which was lower than 14.7%in the control group,and the difference was statistically significant(P<0.05).The Apgar score of newborns in the study group(8.3±0.5)was significantly higher than that in the control group(4.0±0.4)(P<0.05).Conclusion Targeted treatment for patients with gestational diabetes mellitus and effective treatment for patients with premature rupture of membranes can reduce the incidence of adverse outcomes of newborns and improve maternal and infant prognosis,which is worthy of clinical popularization application.