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长链非编码RNA介导的分子调控机制在胰腺癌中的研究进展 被引量：2

Research progress of molecular mechanism mediated by long noncoding RNA in pancreatic cancer
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摘要 胰腺癌具有高度的侵袭性和转移性,发生发展过程中涉及的分子机制十分复杂。近年来,越来越多的胰腺癌相关长链非编码RNA(lncRNA)被发掘,其介导的相应分子生物学作用机制也不断被阐明,为从微观上深入研究胰腺癌提供了新的视角。本文就lncRNA在胰腺癌中发挥作用所介导的分子机制作一综述。 Pancreatic cancer is highly aggressive and metastatic.The molecular mechanisms involved in its development and progression are very complex.In recent years,more and more pancreatic cancer-related long non-coding RNAs(lncRNAs)have been discovered.And the underlying molecular mechanism mediated by them has been elucidated,which provides a microscopic perspective for the in-depth study of pancreatic cancer.In this review,the molecular mechanisms mediated by lncRNAs in pancreatic cancer are reviewed.
作者 陈龙江 汤志刚 Chen Longjiang;Tang Zhigang(Department of Pancreatic Surgery,Renmin Hospital of Wuhan University,Wuhan 430060,China)
机构地区 武汉大学人民医院胰腺外科
出处 《中华实验外科杂志》 CAS 北大核心 2021年第10期2085-2089,共5页 Chinese Journal of Experimental Surgery
基金 国家自然科学基金面上项目(81272740)。
关键词 长链非编码RNA 胰腺癌 分子机制 Long non-coding RNA Pancreatic cancer Molecular mechanism
分类号 R735.9 [医药卫生—肿瘤]
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中华实验外科杂志
2021年 第10期

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