心脏血管肉瘤1例

A Case Report of Cardiac Angiosarcoma

目的探讨心脏血管肉瘤的临床特点、组织学特征、诊断及鉴别诊断。方法分析1例心脏血管肉瘤的临床资料、病理学特征及免疫表型,并复习相关文献。结果镜下可见梭形及上皮样肿瘤细胞,编织状及围绕血管放射状排列,其间可见裂隙状血管及原始血管结构,免疫表型EGR、CD31、CD34弥漫阳性。结论心脏血管肉瘤是较为罕见的恶性肿瘤,预后差,病理形态多样,需与其他肿瘤鉴别。

Objective To investigate the clinical and histological features,diagnosis and differential diagnosis of cardiac angiosarcoma.Methods The clinical data,pathological features and immunophenotype of one case of cardiac angiosarcoma were analyzed,and the related literature was reviewed.Results The fusiform and epithelioid tumor cells were seen under the microscope,woven and radially arranged around the blood vessels,and the fissure-like blood vessels and the original blood vessel structure were seen between them.The immunophenotypes were diffusely positive for EGR,CD31,and CD34.Conclusion Cardiac angiosarcoma is a relatively rare malignant tumor with a poor prognosis and diverse pathological morphology,which needs to be differentiated from other tumors.