调神疏肝针刺法治疗紧张型头痛的疗效及对血清脂联素含量的影响

Effect of Tiaoshen Shugan Acupuncture on Tension-type Headache and Its Influence on Serum Adiponectin Content

目的观察调神疏肝针刺法治疗紧张性头痛病人的疗效及对血清脂联素(APN)含量的影响。方法选取2016年1月—2018年12月内蒙古科技大学包头医学院第二附属医院收治的紧张型头痛(TTH)病人88例,按随机数字表法将TTH病人随机分为调神疏肝针刺组(29例)、传统针刺组(29例)、西药组(30例),选取同时期健康体检者30名为正常组。治疗期间TTH病例脱落5例。调神疏肝针刺组采用调神疏肝、通络止痛法;传统针刺组采用权威教材选穴方案;西药采用阿米替林片,共观察4周。采用视觉模拟评分法(VAS)对头痛程度进行评价,采用酶联免疫吸附法测定调神疏肝针刺组、正常组血清APN含量。结果调神疏肝针刺组、传统针刺组、西药组治疗后VAS评分均较治疗前明显下降(P<0.05);治疗后,调神疏肝针刺组与传统针刺组、西药组比较,VAS评分下降明显(P<0.05)。治疗前,调神疏肝针刺组血清APN含量明显低于正常组(P<0.05);治疗后,调神疏肝针刺组血清APN含量较治疗前明显升高(P<0.05);治疗后,调神疏肝针刺组血清APN含量低于正常组,但差异无统计学意义(P>0.05)。结论调神疏肝针刺法治疗TTH疗效明显,在缓解头痛症状方面明显优于传统针刺法和西药阿米替林。调神疏肝针刺法可提升TTH病人血清APN含量,进而治疗TTH。

Objective To observe the clinical efficacy of Tiaoshen Shugan acupuncture on tesion-type headache and its effect on serum levels of APN.Methods Eighty-eight patients with tension-type headache(TTH)were randomly divided into the Tiaoshen Shugan acupuncture group(n=29),the traditional acupuncture group(n=29),and the amitriptyline group(n=30).Thirty healthy subjects at the same time were selected as the normal control group.In the Tiaoshen Shugan acupuncture group,the methods of Tiaoshen Shugan and pain-relieving were adopted.In the traditional acupuncture group,authoritative textbooks was adopted.The amitriptyline group was given amitriptyline tablets.The course of treatment was 4 weeks.Visual Analogue Scale(VAS)was used to evaluate the severity of headache.Serum APN was determined by enzyme-linked immunosorbent assay.Results Compared with data before treatment,VAS scores in all 3 groups decreased significantly after treatment(P<0.05).Compared with the traditional acupuncture group and the amitriptyline group,VAS value decreased significantly in the Tiaoshen Shugan acupuncture group after treatment(P<0.05).Before treatment,serum APN content in Tiaoshen Shugan acupuncture group was significantly lower than that in the normal group(P<0.05).The serum APN content in the Tiaoshen Shugan acupuncture group was significantly higher than that before treatment(P<0.05).After treatment,serum APN content in the Tiaoshen Shugan acupuncture group was lower than that in the normal group,but there were no difference significant(P>0.05).Conclusion The effect of Tiaoshen Shugan acupuncture is obviously superior to the traditional acupuncture and amitriptyline in alleviating headache symptoms.Tiaoshen Shugan acupuncture can increase the serum APN content of TTH patients.