CRP、SAA、IL-6联合检测在诊断儿童急性扁桃体炎中的临床应用

Clinical application of combined detection of CRP,SAA and IL-6 in the diagnosis of acute tonsillitis in children

目的综合分析CRP(C反应蛋白)、SAA(血清淀粉样蛋白A)、IL-6(白细胞介素-6)联合检测在诊断急性扁桃体炎患儿中的临床应用效果。方法本次研究的疾病为:急性扁桃体炎;患儿共186例,病例的选取时间为2020年1月-2021年1月,按照感染微生物类型分为急性病毒性扁桃体炎组(92例)和急性细菌性扁桃体炎组(94例),再选取本院在2020年1月-2021年1月进行健康体检的186例小儿人群作为对照组。采用统计学分析三组研究对象的CRP水平、SAA水平、IL-6水平以及急性病毒性扁桃体炎患儿和急性细菌性扁桃体炎患儿治疗前后的CRP水平、SAA水平、IL-6水平。结果三组研究对象的CRP水平、SAA水平、IL-6水平差异显著(P<0.05);治疗前,急性病毒性扁桃体炎患儿和急性细菌性扁桃体炎患儿的CRP水平、SAA水平、IL-6水平比较未有显著差异(P>0.05),治疗后急性病毒性扁桃体炎患儿和急性细菌性扁桃体炎患儿的CRP水平、SAA水平、IL-6水平比较差异显著(P<0.05)。结论CRP、SAA、IL-6联合检测在诊断急性扁桃体炎患儿中的临床应用效果显著。

Objective To analyze the clinical application effect of combined detection of CRP(C-reactive protein),SAA(serum amyloid A)and IL-6(interleukin-6)in the diagnosis of children with acute tonsillitis.Methods 186 children with acute tonsillitis were selected from January 2020 to January 2021.They were divided into acute viral tonsillitis group(92 cases)and acute bacterial tonsillitis group(94 cases)according to the type of infection microorganism.Then 186 children with physical examination in our hospital from January 2020 to January 2021 were selected as the control group.The levels of CRP,SAA,IL-6,CRP,SAA and IL-6 of the three groups were statistically analyzed.Result There were significant differences in CRP,SAA and IL-6 levels among the three groups(P<0.05);before treatment,there were no significant differences in CRP,SAA and IL-6 levels between children with acute viral tonsillitis and children with acute bacterial tonsillitis(P>0.05);after treatment,there were no significant differences in CRP,SAA and IL-6 levels between children with acute viral tonsillitis and children with acute bacterial tonsillitis-There was significant difference between the two groups(P<0.05).Conclusion CRP,SAA,IL-6 joint detection in the diagnosis of acute tonsillitis in children with clinical application effect is significant.