不同体质量指数的汉族、哈萨克族人群血脂水平的研究

Study on the blood lipid levels of Han and Kazakhs population with different body mass index

目的探讨汉族、哈萨克族不同体质量指数(BMI)背景下的血脂差异及分布特点,为肥胖相关代谢疾病的防控与诊疗提供依据。方法采用前瞻队列研究方法,选择2020年4-12月新疆生产建设兵团医院及新疆阿勒泰地区人民医院体检人群中的汉族人群950例、哈萨克族人群507例为研究对象。根据BMI分为正常组、超重组、肥胖组,比较两个民族的一般临床资料及不同BMI分组中的血脂情况。结果哈萨克族的体质量、BMI、肥胖检出率均高于汉族,差异有统计学意义(P<0.05),高三酰甘油(TG)血症检出率低于汉族,差异有统计学意义(P<0.05)。正常组哈萨克族总胆固醇(TC)水平与低密度脂蛋白胆固醇(LDL-C)水平均低于汉族,超重组哈萨克族HDL-C水平高于汉族,差异有统计学意义(P<0.05),各BMI分组中哈萨克族TG水平均低于汉族,差异有统计学意义(P<0.05),并且伴随BMI的升高,哈萨克族TG水平增长缓慢且明显低于汉族,差异有统计学意义(P<0.05)。结论哈萨克族可能存在高BMI、低TG水平的血脂分布特点,值得重点关注与探索。

Objective To investigate the differences and distribution characteristics of blood lipids under the background of different body mass index(BMI)of Han and Kazakhs population,and to provide evidence for the prevention,control,diagnosis and treatment of obesity-related metabolic diseases.Methods A prospective cohort study method was used,and a total of 950 Han and 507 Kazakhs people from the Xinjiang Production and Construction Corps Hospital and Xinjiang Altay Regional People′s Hospital from April 2020 to December 2020 were selected as the research objects.According to BMI,they were divided into normal group,overweight group,and obese group.The general clinical data of the two nationalities and the blood lipids under different BMI groups were compared.Results The body weight,BMI and detection rate of obesity of Kazakhs people were higher than those of Han people,and the differences were statistically significant(P<0.05),while the detection rate of hypertriglyceridemia was lower than that of Han people,and the difference was statistically significant(P<0.05).The levels of total cholesterol(TC)and low density lipoprotein cholesterol(LDL-C)of Kazak people in the normal group were lower than those of Han people,the High density liptein cholesterol(HDL-C)level of Kazak people in the overweight group was higher than that of Han people,and the differences were statistically significant(P<0.05),and the triglyceride(TG)level of Kazakh people in each BMI group were lower than those of the Han people,and the differences were statistically significant(P<0.05).And with the increase of BMI,the TG level of Kazakhs people increased slowly and was significantly lower than that of Han people(P<0.05).Conclusion Kazakhs population have the characteristics of high BMI and low TG levels in blood lipid distribution,which is worthy of attention and exploration.