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脂肪因子与阻塞性睡眠呼吸暂停相关性的研究进展

Research progress in the relationship between adipokines and obstructive sleep apnea
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摘要 阻塞性睡眠呼吸暂停(obstructive sleep apnea,OSA)发病率逐年升高,已成为危害人类健康的主要疾病之一。脂肪因子是由脂肪组织分泌的具有多种生物活性的分子,广泛参与到糖脂代谢、炎症反应、免疫应答等过程中,被认为与OSA的发生发展具有密切联系。本文将对部分脂肪因子与OSA相关性的研究进行综述。
作者 郁文俊 易红良 Yu Wenjun;Yi Hongliang(Department of Otorhinolaryngology Head and Neck Surgeiy,Shanghai Jiao Tong University Affiliated Sixth People's Hospital Therapy Center for Obstructive Sleep Apnea,Shanghai 200233,China)
出处 《国际耳鼻咽喉头颈外科杂志》 2021年第5期254-257,共4页 International Journal of Otolaryngology-Head and Neck Surgery
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  • 1魏文青.脂联素的研究现状与展望[J].标记免疫分析与临床,2007,14(2):122-125. 被引量:24
  • 2陈明,李兴.脂联素及其受体表达的调节因素[J].医学综述,2007,13(8):575-577. 被引量:4
  • 3Van Gaal LF, Mertens IL, De Block CE. Mechanisms linking obesity with cardiovascular disease, Nature, 2006, 444(7121): 875-880.
  • 4Kadowaki T, Yamauchi T, Kubota N, et al. Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome, J Clin Invest, 2006, 116 (7): 1784-1792.
  • 5Kadowaki T, Yamauchi T. Adiponectin and adiponectin receptors, Endocr Rev, 2005, 26(3): 439-451.
  • 6Despres JP, Lemieux I. Abdominal obesity and metabolic syndrome, Nature, 2006, 444(7121): 881-887.
  • 7Yamauchi T, Kamon J, Ito Y, et al. Cloning of adiponectin receptors that mediate antidiabetic metabolic effects, Nature, 2003, 423(6941): 762-769.
  • 8Gable DR, Hurel S J, Humphries SE. Adiponectin and its gene variants as risk factors for insulin resistance, the metabolic syndrome and cardiovascular disease, Atherosclerosis, 2006,188(2): 231-244.
  • 9Yamauchi T, Nio Y, Maki T, et al. Targeted disruption of AdipoR1 and AdipoR2 causes abrogation of adiponectin binding and metabolic actions, Nat Med, 2007, 13(3): 332-339.
  • 10Kubota N, Yano W, Kubota T, et al. Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake, Cell Metab, 2007, 6(1): 55-68.

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