铁力木化学成分及药理作用研究进展

Research progress on chemical components and pharmacological effects of Mesua ferrea

铁力木Mesua ferrea为藤黄科铁力木属常绿乔木,其叶子、花、种子及树皮均可作为药用,治疗关节炎、皮肤病、癌症等疾病。国内外学者从铁力木中分离得到黄酮类、香豆素类、三萜类、酚酸类、挥发油类等类型化合物,现代药理学研究表明其具有抗氧化、抗炎、免疫调节、抗癌、抗菌、神经调节等生物活性。对国内外有关铁力木中化学成分和药理研究作用研究进展进行总结,为铁力木的进一步研究和开发利用提供参考。

Mesua ferrea is an evergreen tree of the genus Ferrea in Guttiferae.Different medicinal parts can be used to improve arthritis,skin diseases,cancer and other diseases,including its leaves,flowers,seeds and bark.The chemical components of M.ferrea are flavonoids,coumarins,triterpenes,phenolic acids,volatile oils and so on,which have been shown to have antioxidant,anti-inflammatory,immunomodulatory,anticancer,antibacterial and neuromodulatory activities in modern pharmacological studies.In this paper,the chemical constituents and pharmacological effects of M.ferrea.at home and abroad were summarized to provide reference for further research,development and utilization of M.ferrea.