新型冠状病毒病流行对口腔黏膜鳞癌住院患者延迟就医的影响

Effect of COVID-19 pandemic on patient delay of inpatients with squamous cell carcinoma of oral mucosa

目的 :以2019年和2018年为对照,研究在新型冠状病毒病流行的2020年,口腔黏膜鳞癌住院患者的就医延迟时间是否发生改变。方法:调阅北京大学口腔医院2018—2020年口腔黏膜鳞癌患者的住院电子病历,摘录患者出现首次症状的时间和首次就医时间,计算患者就医延迟时间。采用SPSS 22.0软件包中的非参数秩和检验,分析2020年和2019年、2018年的就医延迟时间的差异。就医延迟时间超过3个月定为延迟就医,以方差分析统计3年延迟就医的发生率的差异。结果:口腔黏膜鳞癌住院患者2020年254例、2019年447例、2018年353例,就医延迟时间的均值分别为3.93个月、4.10个月和4.61个月。非参数秩和检验发现,2020年、2019年、2018年的就医延迟时间差异无统计学意义(P=0.226)。2020年延迟就医的发生率(33.3%)低于2019年(36.5%)和2018年(38.2%),但差异无统计学意义。结论:在新型冠状病毒病流行的2020年,未发现口腔黏膜鳞癌住院患者延迟就医加剧。

PURPOSE: The aim of this research was to investigate whether the pandemic of corona virus disease 2019(COVID-19) had an impact on patient delay of medical management, using 2019 and 2018 as controls. METHODS:Electronic medical records of inpatients with squamous cell carcinoma(SCC) of oral mucosa in 2020, 2019 and 2018 were reviewed, and the time of the first signs or symptoms and the time of initial professional evaluation was extracted. Their interval, namely the patient delay time, was calculated. Nonparametric rank sum test was used to analyze the difference in patient delay time between 2020, 2019 and 2018 with SPSS 22.0 software package. When the delay time was more than 3 months, the patients were grouped as delayed help-seeking. RESULTS: There were 254 inpatients with SCC of oral mucosa in 2020, 447 in 2019, and 353 in 2018. The mean patient delay time was 3.93 months, 4.10 months, and 4.61 months, respectively. Nonparametric rank sum test found that there was no significant difference in the delay time for hos-pitalization in 2020, 2019, and 2018. The rate of delayed help-seeking in 2020 patients was 33.3%, lower than 36.5% in2019 and 38.2% in 2018, but the difference was not significant(P=0.257). CONCLUSIONS: The pandemic of COVID-19 in 2020 probably had no effect on patient delay time for treatment of SCC of oral mucosa.