急性胰腺炎诱发心血管系统损伤的研究进展

Research progress of cardiovascular system injury induced by acute pancreatitis

急性胰腺炎(AP)是胰腺组织的急性化学性炎症,以自身消化所致的胰腺水肿、出血及坏死等损伤为特点,是临床上较常见的消化系统疾病。研究发现AP均伴有心血管系统损伤,损伤程度与AP的严重程度呈正相关。AP诱发心血管系统损伤目前以对症支持治疗为主,控制AP本身是疾病治疗的重点。笔者就AP诱发心血管损伤的临床表现及相关机制的研究进展进行阐述,以期为及时预防AP诱发心血管系统损伤以及降低AP病死率提供新的思路。

Acute pancreatitis(AP) is an acute chemical inflammation of the pancreas, characterized by pancreatic edema, bleeding and necrosis caused by internal digestion, and it is a relatively common digestive system disease in clinical practice. Studies have found that AP is associated with cardiovascular system injury,and the degree of injury is positively correlated with the severity of AP. At present, the symptomatic supportive treatment is the main therapeutic approach for AP, and the control of pancreatitis itself is the focus of treatment. Here, the authors address the clinical manifestations of AP-induced cardiovascular injury and the research progress of relevant mechanisms, so as to provide new ideas for timely preventing AP-induced cardiovascular injury as well as reducing the mortality rate of AP.