成人血清IL-1β、IL-2r、IL-6、IL-8和IL-10正常参考区间的建立

Establishment of adult reference intervals for interleukin-1β,interleukin-2r,interleukin-6,interleukin-8 and interleukin-10 in serum

目的建立成人血清IL-1β、IL-2r、IL-6、IL-8和IL-10正常参考区间。方法收集健康体检者180例,利用Immulite 1000自动化学发光免疫分析仪检测血清IL-1β、IL-2r、IL-6、IL-8和IL-10的水平。结果成人血清IL-1β、IL-2r、IL-6、IL-8和IL-10的95%正常参考区间分别为:<5 pg/mL、<572 U/mL、<2 pg/mL、<70.5 pg/mL和<5 pg/mL。结论初步建立本实验室Immulite 1000自动化学发光免疫分析仪成人血清IL-1β、IL-2r、IL-6、IL-8和IL-10正常参考区间。

Objective To establish of adult reference intervals for interleukin-1β,interleukin-2r,interleukin-6,inter-leukin-8,and interleukin-10 in serum.Methods Serum specimens were collected from 180 cases of healthy individuals.The serum levels of IL-1β,IL-2r,IL-6,IL-8 and IL-10 were measured by Immulite 1000 automatic chemiluminescent immunoassay.Results The 95%reference intervals of IL-1β,IL-2r,IL-6,IL-8 and IL-10 were〈5 pg/mL,〈572 U/mL,〈2 pg/mL,<70.5 pg/mL and<5 pg/mL respectively.Conclusion The normal reference intervals of IL-1β,IL-2r,IL-6,IL-8,and IL-10 in adult serum of Immunolite 1000 automatic chemiluminescent immunoassay in our laboratory were preliminarily established.