针灸联合中药治疗多囊卵巢综合征31例

Effects of acupuncture combined with traditional Chinese medicine in patients with polycystic ovary syndrome

目的探讨针灸联合中药治疗多囊卵巢综合征(PCOS)的临床效果。方法选取2016年1月至2019年1月海口市人民医院收治的经病理学与影像学诊断确诊的PCOS病人60例,在观察其排卵特点的基础上按随机数字表法分为A、B组,其中A组(31例)予以针灸联合中药治疗,B组(29例)单纯予以西药(炔雌醇环丙孕酮片+氯米酚)治疗,比较两组临床疗效。结果A组子宫内膜厚度[(9.57±1.35)mm比(7.23±1.24)mm]、优势卵泡数量[(2.75±1.90)个比(1.35±1.05)个]、卵泡总数量[(6.11±0.85)个比(4.05±0.53)个]显著优于B组(P<0.05),卵泡生长时间[(17.55±2.34)d比(17.02±2.81)d]与B组相比差异无统计学意义(P>0.05)。A组排卵率(100.00%比82.76%)、妊娠率(51.61%比34.48%)显著高于B组,早期流产率(3.23%比13.79%)低于B组(P<0.05)。A、B组治疗前的卵泡刺激素(FSH)、黄体生成素(LH)、睾酮(T)、LH/FSH比较,差异无统计学意义(P>0.05),两组治疗后均优于治疗前,且A组显著优于B组(P<0.05)。A组月经紊乱、闭经、不孕改善有效率分别为96.77%、100.00%和93.55%,B组分别为86.21%、86.21%和82.76%,A组均显著优于B组(P<0.05)。结论PCOS病人的排卵特点在临床中常表现为月经周期延长、体质量指数超标、卵泡个数增多等,针对该病的这些排卵特点科学、合理的予以针灸联合中药治疗效果较好,无副作用、成本低廉。

Objective To investigate the clinical effect of acupuncture combined with traditional Chinese medicine(TCM)in pa‐tients with polycystic ovary syndrome(PCOS).Methods Sixty patients with PCOS diagnosed by pathology and imaging in Haikou Peo‐ple's Hospital from January 2016 to January 2019 were selected.On the basis of observing their ovulatory characteristics,they were as‐signed into group A and group B according to a random number table.Among them,group A(31 cases)was treated with acupuncture combined with traditional Chinese medicine,while group B(29 cases)was treated with western medicine alone(estrinol cyclopropa‐none tablets+clomiphene).The clinical effects of the two groups were compared.Results The endometrial thickness[(9.57±1.35)mm vs.(7.23±1.24)mm],the number of dominant follicles[(2.75±1.90)vs.(1.35±1.05)]and the total number of follicles[(6.11±0.85)vs.(4.05±0.53)]in group A were significantly better than those in group B(P<0.05).There was no significant difference in follicular growth time compared with group B[(17.55±2.34)d vs.(17.02±2.81)d,P>0.05].The ovulation rate(100.00%vs.82.76%)and pregnancy rate(51.61%vs.34.48%)in group A were significantly higher than those in group B.The early abortion rate was lower than that in group B(3.23%vs.13.79%),the difference was statistically significant(P<0.05).There was no significant difference in follicle stimulating hor‐mone(FSH),luteinizing hormone(LH),testosterone(T)and LH/FSH between groups A and B(P>0.05),but the two groups were signifi‐cantly better than before treatment,and group A was significantly better than group B(P<0.05).The effective rate of menstrual disor‐ders,amenorrhea and infertility in group A was 96.77%,100.00%and 93.55%,respectively,and in group B was 86.21%,86.21%and 82.76%,respectively.The three indicators in group A were significantly better than group B(P<0.05).Conclusion The ovulatory char‐acteristics of PCOS patients are prolonged menstrual cycle,excessive BMI and increased number of follicles in clinic.In view of these ovulatory characteristics of the disease,acupuncture and moxibustion combined with traditional Chinese medicine have good therapeu‐tic effect,no side effects and low cost.