摘要
制备了用于立体光固化技术(SL)的ZrO_(2)浆料,采用SL打印制备了ZrO_(2)生物陶瓷,研究了烧结样品的力学性能与生物相容性。经过不同温度烧结后,ZrO_(2)原粉中的m-ZrO_(2)均完成了向t-ZrO_(2)或c-ZrO_(2)的转变。随着烧结温度的提高,陶瓷致密化程度提高,气孔数量减少;当烧结温度继续提高时,晶粒尺寸继续增大且大小不均匀。当烧结温度从1450℃升高至1600℃时,ZrO_(2)生物陶瓷的维氏硬度和断裂韧性先增大后减小,且均在1500℃达到最大值,分别为14.87 GPa和6.73 MPa·m^(1/2),此时的线收缩率与相对密度分别为23.42%和97.32%。同时利用大鼠骨髓间充质干细胞(rBMSCs)进行体外细胞实验,证明了SL成形的ZrO_(2)生物陶瓷具有较好的生物相容性,在牙科修复中具有广阔的应用前景。
In order to use ZrO_(2) all-ceramic restorations in the dental field,ZrO_(2) slurry suitable for SL technology was obtained and ZrO_(2) bioceramic was prepared by SL.The mechanical properties and biocompatibility were investigated.The transformation from m-ZrO_(2) to t-ZrO_(2) or c-ZrO_(2) in the original ZrO_(2) powder was completed when sintered at different temperatures.The density of ceramic increases and the number of pores decreases as the sintering temperature increases,and the grain size increases and becomes uneven when the temperature further increases.The Vickers hardness and fracture toughness of ZrO_(2) bioceramic firstly increase and then decrease when the sintering temperature increases from 1450℃to 1600℃,and they reach their maximum values(i.e.,14.87 GPa and 6.73 MPa·m^(1/2))at 1500℃.The linear shrinkage and relative density are 23.42%and 97.32%,respectively.In addition,rat bone marrow mesenchymal stem cells(rBMSCs)were used for in vitro cell experiments,thus proving that ZrO_(2) bioceramic fabricated by SL technique have a good biocompatibility,which can have some application prospects in dental restoration.
作者
陈芬
吴亚茹
朱皓
吴甲民
肖骏
史玉升
CHENFen;WU Yaru;ZHU Hao;WU Jiamin;XIAO Jun;SHI Yusheng(State Key Laboratory of Materials Processing and Die&Mould Technology,School of Materials Science and Engineering,Huazhong University of Science and Technology,Wuhan 430074,China;Engineering Research Center of Ceramic Materials for Additive Manufacturing,Ministry of Education,Wuhan 430074,China;Department of Orthopedic Surgery,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,1095 Jiefang Avenue,Wuhan 430030,China)
出处
《硅酸盐学报》
EI
CAS
CSCD
北大核心
2021年第9期1837-1845,共9页
Journal of The Chinese Ceramic Society
基金
国家重点研发计划(2018YFB1105503)
湖北省技术创新专项重大项目(2019AAA002)。
关键词
增材制造
氧化锆
立体光固化
力学性能
生物相容性
additive manufacturing
zirconia
stereolithography
mechanical properties
biocompatibility