摘要
Alzheimer’s disease(AD)is the most common type of neurodegenerative dementia worldwide[1].Deposition of extracellular amyloid proteinβ(Aβ)-producing amyloid plaques and intracellular tau aggregation-comprising neurofibrillary tangles are two typical pathological features of this disease.
基金
supported by grants from the National Nature Science Foundation of China[NO.82030064,81871714]
Beijing Municipal Administration of Hospital’s Ascent Plan[DFL20180803]
Beijing Key Clinical Specialty Construction Project
Key Medical Specialties of"Sailing"Program[NO.ZYLX202114]。
