痰湿现代医学本质述析

Discussion on The Modern Medical Nature of Phlegm Dampness

中医学认为“痰湿”与冠心病、糖尿病、肥胖等多种临床常见疾病关系密切,是中医学特色病因及病理产物之一。本文意在探析痰湿的现代医学基础,基于生物学基础、病理学特征以及生物信息学,揭示痰湿是多种疾病病理改变的关键因素,认为痰湿的病理学特征主要与水液代谢异常、血脂代谢异常、炎症反应、物质能量代谢异常、免疫调节异常有关,涉及神经、免疫等多个系统,与现代生物信息学中的蛋白质、糖、脂质这三大物质代谢及基因组学相关,其代谢产物等可作为诊断痰湿证的客观化指标,基于微观物质基础揭示出“痰湿”现代医学本质,对系统分析痰湿致病的发病机制有重要的指导作用,为中医临床针对“痰湿”异病同治提供一定的研究方向及科学依据。

Traditional Chinese medicine holds that phlegm dampness is closely related to many common clinical diseases such as coronary heart disease,diabetes and obesity.It is one of the etiological factors and pathological products of TCM.This paper aims to explore the modern medical basis of phlegm dampness.Based on the biological basis,pathological characteristics and bioinformatics,it reveals that phlegm dampness is the key factor of pathological changes of many diseases.It is believed that the pathological characteristics of phlegm dampness are mainly related to abnormal water and lipid metabolism,inflammatory reaction,abnormal material and energy metabolism and abnormal immune regulation,it involves nervous system,immune system and so on,It is related to the metabolism of protein,sugar and lipid in modern bioinformatics and genomics.Its metabolites can be used as objective indicators for the diagnosis of phlegm dampness syndrome,revealing the essence of modern medicine based on micro material basis.It has an important guiding role for the systematic analysis of the pathogenesis of phlegm dampness,and provides a certain research direction and scientific basis for the clinical treatment of"phlegm dampness"with different diseases.