内科老年重症心力衰竭临床治疗的疗效分析

Clinical Analysis of Clinical Treatment for Elderly Patients with Severe Heart Failure

目的研究并分析内科老年重症心力衰竭患者的临床治疗效果。方法抽取我院内科收治的90例老年重症心力衰竭患者作为研究对象,其中30例设为A组(应用常规抗心力衰竭药物治疗),30例设为B组在(A组基础上增加诺欣妥治疗),30例设为C组(在B组基础上增加美托洛尔治疗),比较3组老年重症心力衰竭患者的心功能、左心室射血分数、脑钠肽等指标变化情况,对比3组随访结果。结果治疗6个月后,B、C两组心功能、左心室射血分数、β型脑钠肽等水平明显优于治疗前,B、C两组改善水平优于A组,C组β型脑钠肽下降辐度优于B组,C组各项指标改善水平优于A组、B组,对比有显著差异(P<0.05);随访6个月后,C组、B组两组住院次数、病死率均低于A组,对比有显著差异(P<0.05);心率恢复时间、气喘缓解时间、水肿消退时间与住院时间指标对比,C组最佳、其次为B组,两两对比存在差异(P<0.05)。结论内科老年重症心力衰竭患者接受β受体阻滞剂、血管紧张素Ⅱ受体抑制剂等药物治疗,能提高临床治疗效果,进而对患者预后具有较好的改善作用。

Objective To study and analyze the clinical treatment effect of elderly patients with severe heart failure in internal medicine.Methods Ninety elderly patients with severe heart failure admitted to our hospital were enrolled in the study.Among them,30 cases were set as group A to be treated with conventional anti-heart failure drugs,30 cases were set as group B to add nuoxinto treatment on the basis of group A,and 30 cases were set as group C to be treated with metoprolol on the basis of group B.The changes of cardiac function,left ventricular ejection fraction,brain natriuretic peptide and other indicators in 3 groups of elderly patients with severe heart failure were compared.Results After 6 months of treatment,the levels of cardiac function,left ventricular ejection fraction,and brain natriuretic peptide in group B and C were significantly better than those before treatment.The improvement in group B and C was better than that in group A.Group C brain natriuretic peptide the descending amplitude was better than that of group B.The improvement of each index in group C was better than that in group A and group B.The difference was significant(P<0.05).After 6 months of follow-up,the number of hospitalizations and death in group C and group B were the same.The rates were lower than those in group A,and there was a significant difference(P<0.05).Compared with the indexes of heart rate recovery time,asthma remission time,edema regression time and hospitalization time,group C was the best,followed by group B.There was a difference between the two groups(P<0.05).Conclusion Patients with severe heart failure in the elderly with β-blockers and angiotensin II receptor inhibitors can improve the clinical treatment effect and improve the prognosis of patients.