颈椎Modic改变影响因素及其临床意义的研究进展

Progeress of affecting factors and clinical significance in Modic changes of cervical spine

颈椎Modic改变即颈椎间盘软骨终板及终板下骨髓在MRI不同加权像下的异常信号改变。颈椎Modic的发生受众多因素影响,颈椎间盘的退变程度是目前被多数学者认可的与颈椎Modic改变相关性最高的影响因素,其他因素如性别、年龄及颈痛等与颈椎Modic改变是否存在相关性仍有争议。颈椎Modic改变可能是降低非手术治疗疗效的危险因素之一。术前是否存在颈椎Modic改变可能对手术结果无明显影响,但对术后早期植骨融合率、有症状ASD的发生及术后轴性症状的出现可能产生影响。

Modic changes of cervical spine are abnormal singal changes of vertebral endplate and subchondral bone marrow in different weighted images of MRI.The degree of cervical disc degeneration is currently recognized by most scholars as the influencing factor with the highest correlation with cervical Modic changes.Whether other factors such as gender,age and neck pain are related to cervical Modic changes is still controversial.Modic changes of cervical spine may be one of the risk factors to reduce the efficacy of non-surgical treatment.The presence of Modic changes in the cervical spine may not have a significant impact on the outcome of surgery,but the fusion rate of early postoperative bone graft,the occurrence of symptomatic ASD and the axial symptoms may be affected.