丙泊酚联合不同剂量地佐辛应用于无痛人工流产的效果比较

Comparison of the effect of propofol combined with different doses of dezocine on painless induced abortion

目的:探讨丙泊酚联合不同剂量地佐辛应用于无痛人工流产的效果。方法:选取120例无痛人工流产患者,随机分为A组、B组、C组各40例。3组均使用丙泊酚,此外,A、B、C组分别联合使用地佐辛0.05 mg/kg、0.075 mg/kg、0.1 mg/kg。比较3组围术期指标、麻醉效果、术后宫缩疼痛程度、不良反应发生率。结果:3组意识消失时间对比无统计学意义(P>0.05),但组别、时点、组别·时点VAS评分比较具有统计学意义(P<0.05);B、C组麻醉显效率高于A组,而注射疼痛发生率低于A组(P<0.05)。结论:丙泊酚联合0.075 mg/kg地佐辛用于无痛人工流产麻醉效果显著。

Objective:To investigate the effect of propofol combined with different doses of dezocine in the application of painless induced abortion.Methods:One hundred and twenty patients with painless induced abortion were selected and randomly divided into group A,B and C with 40 cases each.Propofol was all used in 3 groups,in addition,different doses of dezocine were used in group A(0.05 mg/kg),B(0.075 mg/kg),C(0.1 mg/kg).The perioperative indicators,the anesthetic effect,the uterine contraction pain after operation,the incidence of adverse reactions were compared among the three groups.Results:Comparison of the time for consciousness disappearance showed no statistical significance(P>0.05),however VAS scores in the three groups,at the time points and the groups and time points showed statistical significance(P<0.05).The anesthetic effect rate was higher while the incidence of injection pain was lower in group B and C than group A(P<0.05).Conclusion:Propofol combined with 0.075 mg/kg dezocine for the painless induced abortion has significant anesthetic effect.