中国胰腺癌流行病学、危险因素及筛查现况

Present Status of Epidemiology,Risk Factors and Screening of Pancreatic Cancer in China

胰腺癌是全球最致命的肿瘤之一,2020年全球肿瘤登记数据显示,胰腺癌发病率位居全球肿瘤发病率的第12位,但死亡率却高居恶性肿瘤死亡第7位,其发展迅速,预后极差,5年生存率极低。我国的胰腺癌疾病负担与西方国家存在较大差异,说明遗传因素、生活方式和环境等危险因素在地区间的分布有所不同。本研究回顾了中国胰腺癌的流行病学、病因研究及筛查现况,为制定适合我国的胰腺癌防治策略和措施提供系统参考。

Pancreatic cancer(PC)is one of most fatal cancers worldwide.According to the 2020 cancer registry data,PC was the 12th common cancer and the 7th leading cause of cancer deaths globally.PC is a rare cancer,but the 5-year survival is very low because of its rapid progress and poor prognosis.The disease burden of PC in China is quite different from western countries,indicating that the distribution of genetic factors,lifestyle and environmental factors varies from different regions.This article reviews the epidemiology,etiology and screening of PC in China,to provide systematic references for PC prevention and control.