超声颈-股脉搏波传导速度早期评价糖尿病患者血管弹性

Early evaluation of vascular elasticity by ultrasonic cervical-femoral pulse wave velocity in diabetic patients

目的探讨超声测量颈-股脉搏波传导速度(CF-PWV)用于早期评价糖尿病患者动脉弹性的可行性。方法采用超声设备内置整体动脉僵硬度自动测量系统测量107例糖尿病患者、72例正常人CF-PWV,绘制ROC曲线图。结果糖尿病组CF-PWV参数明显高于正常组(P<0.01),斑块组CF-PWV参数高于无斑块组(P<0.05)。ROC曲线下面积为0.76,特异度、敏感度分别为90.3%、56.2%。结论糖尿病患者全身动脉弹性减低出现早,超声可安全、无创、精确检测CF-PWV。

Objective To study the feasibility of ultrasonic carotid-femoral pulse wave velocity(CF-PWV)in early evaluation of arterial elasticity in patients with diabetes mellitus(DM).Methods CF-PWV in 107 DM patients and 72 healthy controls was measured using Doppler ultrasonography with built-in automatic measurement of arterial stiffness.The cut-off value of CF-PWV was calculated using ROC curve.Results CF-PWV parameters were higher in DM group than in control group(P<0.01),and so did between DM patients with and without plaque(P<0.05).The area under ROC curve was 0.76,with 90.3%of specificity and 56.2%of sensitivity.Conclusion The reduced systemic arterial elasticity occurs early in diabetic patients.Ultrasound is safe,non-invasive,and accurate in detecting CF-PWV.