西安地区5岁以下儿童轮状病毒胃肠炎与大气环境的相关性分析

Correlation between Rotavirus Gastroenteritis and Atmospheric Environment in Children under 5 Years Old in Xi'an

【目的】探讨西安地区5岁以下儿童轮状病毒(Rotavirus,RV)感染性腹泻与大气环境的相关性。【方法】回顾性分析西安市儿童医院2017年1月至2019年1月粪便常规RV和(或)腺病毒(adeno virus,AV)检测阳性的住院患儿的临床资料,分析西安地区2017-2019年患儿粪便RV和腺病毒检测情况,从西安市生态环境局获取每月的大气数据进行统计分析,分析大气污染物颗粒对患儿RV、AV感染的相关性。【结果】西安地区RV检测阳性患儿中男性多于女性,年龄主要集中于3岁以下,以1〜3岁最为多见,新生儿RV感染呈上升趋势。AV检测阳性患儿以1〜3岁最为多见,呈上升趋势。西安地区每月的NO_(2)、PM_(10)、SO_(2)和PM_(2.5)等大气污染物颗粒的浓度水平与每月住院患儿RV感染呈显著正相关,差异有统计学意义(均P<0.05)。【结论】西安地区RV感染主要多见于3岁以下患儿,大气污染颗粒可能会加重RV感染性腹泻的发生。

【Objective】To explore the correlation between rotavirus(RV)infectious diarrhea and atmospheric environment in children under 5 years old in Xi'an.【Methods】The clinical data of hospitalized children with positive stool routine RV and/or adenovirus(AV)in Xian childrens Hospital from January 2017 to January 2019 were analyzed retrospectively,and the Stool RV and adenovirus detection of children in Xi'an from 2017 to 2019 were analyzed,The monthly air data were obtained from Xi'an ecological environment bureau to statistically analyze the correlation between air pollutant particles and RV and AV infection in children.【Results】There were more males than females in children with positive RV test in Xian.The age was mainly under 3 years old,most of them were 1〜3 years old.Neonatal RV infection showed an upward trend,as shown in Table 1.AV positive children aged 1〜3 years were the most common,showing an upward trend.The monthly concentrations of NO_(2),PM_(10),SO_(2)and PM_(2.5)in Xian were significantly positively correlated with RV infection in hospitalized children every month(Mean P<0.05).【Conclusion】RV infection is mainly found in children under 3 years old in Xi'an.Air pollution particles may aggravate the occurrence of RV infectious diarrhea.