抗乙型肝炎病毒药物研究进展与发展趋势

Research Progress and Development Trend of Anti-hepatitis B Virus Drugs

乙型肝炎病毒感染是全球性健康问题,因其较高的发病率和死亡率而引起广泛关注。目前已上市的抗乙型肝炎病毒药物未能达到理想疗效,且存在较高的耐药性和不良反应。随着对抗乙型肝炎病毒药物作用机制的深入研究,许多药物进入临床试验阶段,并且乙型病毒性肝炎治疗理念也得到不断更新。该文综述抗乙型肝炎病毒药物的研究进展与发展趋势,以期为临床治疗提供参考。

Hepatitis B virus infection is a global problem of public health,which has provoked widespread concern due to its high morbidity and mortality.Currently,many drugs for treating hepatitis B have appeared on the market,but have not achieved the desired therapeutic effect.At the same time,a lot of drugs generally possess the disadvantage of high drug resistance and adverse reactions.With the in-depth study of the mechanism of hepatitis B virus,a large amount of drugs are in the clinical research stage,and the treatment concept of hepatitis B is constantly updated.In this paper,we reviewed the recent researches of new anti-hepatitis B virus drugs,in order to provide references for clinical treatment.