黄蜡果果实化学成分研究

Chemical Constituents from the Fruits of Stauntonia brachyanthera

目的:研究黄蜡果Stauntonia brachyanthera Hand.Mazz.果实的化学成分。方法:采用多种柱色谱进行分离纯化,并结合核磁共振、质谱数据及理化性质鉴定化合物的结构。结果:从黄蜡果果实95%的乙醇提取物中共分离得到14个化合物,分别鉴定为:齐墩果酸(1)、松叶菊萜酸(2)、20α⁃hydroxyl⁃29⁃noroleanolic acid(3)、木通萜酸(4)、prosapogenin cp2b(5)、常春藤皂苷元⁃β⁃D⁃吡喃木糖基(1→2)α⁃L⁃阿拉伯吡喃糖苷(6)、3,4⁃二羟基苯甲酸(7)、cryptochlorogenic acid methyl ester(8)、3,5⁃二咖啡酰奎尼酸甲酯(9)、豆甾醇(10)、β⁃胡萝卜苷(11)、cholest⁃5⁃en⁃3β⁃ol(12)、姜糖脂B(13)、2⁃亚油酸甘油酯(14)。结论:其中,化合物2~10、12、13为首次从黄蜡果中分离得到。

Objective:To study the chemical constituents from fruits of Stauntonia brachyanthera.Methods:The compounds were i⁃solated and purified by column chromatography,the structures were identified through NMR,MS data and physicochemical properties.Results:Fourteen compounds were isolated from the 95%ethanol extract of fruits of Stauntonia brachyanthera,and identified as oleanolic acid(1),mesembryanthemoidigenic acid(2),20α⁃hydroxyl⁃29⁃noroleanolic acid(3),akebonoic acid(4),prosapogenin cp2b(5),saponin B(6),protocatechuic acid(7),cryptochlorogenic acid methyl ester(8),methyl 3,5⁃dicoffeoquinic acid(9),stigmas⁃terol(10),β⁃daucosterol(11),cholest⁃5⁃en⁃3β⁃ol(12),gingerglycolipid B(13),2⁃monolinolein(14),respectively.Conclusion:Among them,compounds 2 to 10,12,13 are isolated from Stauntonia brachyanthera for the first time.