贵阳市MSM中HIV TP HSV-2感染及合并感染情况

Current HIV,TP and HSV-2 infection status and co-infection in MSM population in Guiyang

目的了解贵阳市MSM中HIV、TP及HSV-2的流行状况及相关影响因素。方法通过同伴推动抽样法招募MSM为调查对象,对其社会人口学特征进行分析;进行HIV、TP及HSV-2感染检测;并分析其实验室检测结果。结果 577例研究对象中,共发现HIV抗体阳性者、TP特异性抗体阳性者及HSV-2抗体阳性者116例(20.1%)、107例(18.5%)、74例(12.8%);HIV+TP、HIV+HSV-2、TP+HSV-2以及HIV+TP+HSV-2合并感染者依次为24例(4.2%)、8例(1.4%)、11例(1.9%)、20例(3.5%)。HIV感染率在不同年龄组、职业及婚姻状况间的差异有统计学意义;TP感染率在不同文化程度、职业及婚姻状况间的差异有统计学意义;HSV-2感染率在不同年龄、文化程度及婚姻状况间的差异有统计学意义;HIV+TP、HIV+TP+HSV-2、TP+HSV-2等3种类型的合并感染率在不同文化程度以及不同婚姻状况间的差异有统计学意义。结论贵阳市MSM中HIV、TP及HSV-2的感染率较高,合并感染情况较为严重,防治形势严峻,应加强本地区MSM的HIV、TP及HSV-2防治工作;同时应结合实验室检测结果制订相关干预措施,及早进行抗病毒治疗。

Objective To understand the current prevalence of HIV,TP and HSV-2 among men who have sex with men(MSM) in Guiyang.Methods MSM were recruited as survey objects using respondent-driven sampling method,and their social demographic characteristics were analyzed.The MSM people were tested for HIV,TP and HSV-2 followed by analysis of the laboratory test results.Results A total of 116(20.1%),107(18.5%) and 74(12.8%) individuals with HIV antibody positive,TP-specific antibody positive and HSV-2 antibody positive was found in 577 objects of study.There were 24(4.2%) cases for HIV+TP co-infection,8(1.4%) cases for HIV+HSV-2 co-infection,11(1.9%) cases for TP+HSV-2 co-infection and 20(3.5%) cases for HIV+TP+HSV-2 co-infection.Univariate analysis of related factors indicated that prevalence of HIV had statistically significant differences among different age groups,occupations and marital status,while prevalence of TP among different educational level,occupation and marital status and statistically significant differences were found in prevalence of HSV-2 among different age,education level and marital status.Three types of co-infections including HIV+TP,HIV+TP+HSV-2 and TP+HSV-2 showed statistically significant differences among different education levels and marital status.Conclusion The infection rates of HIV,TP and HSV-2 were relatively high and those of their co-infections were serious among MSM in Guiyang.In view of the serious situation of prevention and treatment,the prevention and treatment of HIV,TP and HSV-2 among the MSM population in this region should be strengthened.At the same time,relevant intervention measures should be formulated in combination with laboratory test results and early antiviral treatment should be taken.