天麻钩藤饮联合耳尖放血辅助治疗阴虚阳亢型高血压急症、亚急症临床研究

Clinical Study on Tianma Gouteng Yin Combined with Ear Apex Bloodletting for Adjuvant Therapy of Hypertension Emergencies and Urgencies of Yin Deficiency with Yang Hyperactivity Type

目的:观察天麻钩藤饮联合耳尖放血辅助治疗阴虚阳亢型高血压急症、亚急症的临床疗效。方法:选取75例阴虚阳亢型高血压急症、亚急症患者,按随机数字表法分为观察组40例与对照组35例。对照组采取常规西药治疗,观察组在对照组的基础上给予天麻钩藤饮联合耳尖放血治疗。治疗7 d后,观察比较2组临床疗效、中医证候积分、血压水平、住院时间及安全性。结果:治疗后,观察组总有效率为95.00%,对照组为74.29%,2组比较,差异有统计学意义(P<0.05)。治疗后,观察组住院时间短于对照组,差异有统计学意义(P<0.05)。治疗前,2组中医证候积分比较,差异无统计学意义(P>0.05);治疗后,2组中医证候积分均低于治疗前(P<0.05),且观察组中医证候积分低于对照组(P<0.05)。治疗前,2组收缩压(SBP)、舒张压(DBP)及平均脉动压水平比较,差异无统计学意义(P>0.05);治疗后,2组各时间点SBP、DBP及平均动脉压水平均较治疗前降低(P<0.05);且观察组治疗后各个时间点的SBP、DBP及平均动脉压水平均低于对照组(P<0.05);2组治疗前后经血、尿、大便常规及肝肾功能检查均未出现异常,治疗期间未发生任何不良反应。结论:采用天麻钩藤饮联合耳尖放血辅助治疗阴虚阳亢型高血压急症、亚急症临床疗效显著,可有效缓解患者临床症状,降低血压水平,缩短住院时间,且安全性良好。

Objective:To observe the clinical effect of Tianma Gouteng yin combined with ear apex bloodletting for adjuvant therapy of hypertension emergencies and urgencies of yin deficiency with yang hyperactivity type.Methods:A total of 75 cases of patients with hypertension emergencies or urgencies of yin deficiency with yang hyperactivity type were selected and divided into the observation group and the control group according to the random number table method,40 and35 cases in each group respectively.The control group was treated with routine western medicine,and the observation group was additionally treated with ear apex bloodletting and Tianma Gouteng yin based on the treatment of the control group.After seven-day treatment,clinical efficacy,TCM syndrome score,blood pressure level,hospitalization time,as well as safety were observed and compared between the two groups.Results:After treatment,the total effective rate was 95.00%in the observation group,and 74.29%in the control group,the difference being significant(P<0.05).After treatment,the hospitalization time in the observation group was shorter than that in the control group,the difference being significant(P<0.05).Before treatment,there was no significant difference being found in the comparison of Chinese medicine syndrome scores between the two groups(P>0.05).After treatment,Chinese medicine syndrome scores in the two groups were decreased when compared with those before treatment(P<0.05),and the score in the observation group was lower than that in the control group(P<0.05).Before treatment,when compared levels of systolic blood pressure(SBP),diastolic blood pressure(DBP),and mean pulsation pressure between the two groups,there was no significance being found in the difference(P>0.05).After treatment,levels of SBP,DBP and mean pulsation pressure at each time point in the two groups were decreased when compared with those before treatment(P<0.05),and the three levels at each time point in the observation group were lower than those in the control group(P<0.05).During treatment,there was no obvious adverse reaction in the two groups.Conclusion:Tianma Gouteng yin combined with ear apex bloodletting has a significant clinical effect on the adjuvant therapy of hypertension emergencies and urgencies of yin deficiency with yang hyperactivity type.It can effectively relieve clinical symptoms,reduce blood pressure level,and shorten hospitalization time,with good safety.