急性阑尾炎患者血清IAP、CRP水平的检测意义分析

Analysis of the Significance of Detection of Serum IAP and CRP in Patients With Acute Appendicitis

目的探讨急性阑尾炎患者血清免疫抑制酸性蛋白(IAP)、C反应蛋白水平的检测意义。方法选择2019年3月-2020年3月收治的86例急性阑尾炎患者,将其纳入观察组,选择同期90例健康体检者,将其纳入对照组,检测两组血清IAP、CRP水平,根据术后病理诊断结果将观察组分为单纯型、化脓型、坏疽穿孔型3个亚组,观察不同病理类型急性阑尾炎患者IAP、CRP水平。结果观察组患者IAP、CRP水平与对照组比较,明显更高,差异有统计学意义(P<0.05);坏疽穿孔型IAP、CRP水平与化脓型、单纯型比较,明显更高,差异有统计学意义(P<0.05);观察组行阑尾切除术,观察组术后2 dIAP、CRP水平明显高于术前,术后5 dIAP、CRP水平明显低于术后2 d,均差异有统计学意义(P<0.05)。结论检测血清IAP、CRP水平可助于急性阑尾炎诊断,并可评估其病情严重程度。

Objective To explore the significance of serum immunosuppressive acidic protein(IAP)and C-reactive protein levels in patients with acute appendicitis.Methods 86 patients with acute appendicitis admitted from March 2019 to March 2020 were selected and included in the observation group,select 90 healthy people in the same period and include them in the control group,detection of serum IAP and CRP levels in two groups,according to the results of postoperative pathological diagnosis,the observation group was divided into three subgroups:simple,suppurative,and gangrene perforated,observe the levels of IAP and CRP in patients with different pathological types of acute appendicitis.Results Compared with the control group,the levels of IAP and CRP in patients with acute appendicitis were significantly higher(P<0.05);The levels of gangrene perforated,suppurative IAP and CRP were significantly higher than those of simple type(P<0.05),the gangrene perforated IAP and CRP were significantly higher than those of suppurative type(P<0.05);The observation group underwent appendectomy,the 2 dIAP and CRP levels in the observation group after operation were significantly higher than those before operation,he levels of IAP and CRP at 5 d postoperatively were significantly lower than those at 2 d postoperatively(P<0.05).Conclusion Detection of serum IAP and CRP levels can aid in the diagnosis of acute appendicitis and can assess the severity of its condition.