光学活性的醛酮鉴定试剂

AN OPTICALLY ACTIVE IDENTIFICATION REAGENT FOR ALDEHYDES AND KETONES

醛酮鉴定试剂很多,利用肼基与羰基缩合的尤其常用,如苯肼、氨基脲等等。杨石先等的工作表明,处于肼基二硫代甲酸酯(NH2NH-C-SR)中的肼基同样容易和羰基缩合。我们用N-氯甲基-d-樟脑酰亚胺合成了肼基二硫代甲酸-d-樟脑酰亚胺甲基酯(Ⅰ)。

D-Camphorimido-methyl dithiocarbazate ■:(Ⅰ)has been synthesized.It can condense with various aldehydes and keto-nes.Fourteen carbonyl derivatives of(Ⅰ)were prepared and their physical constantes have been determined.Except aliphatic aldehydes,most carbonyl compounds give stable crystalline derivatives with sharp melting points and definite specific rotations.Thus(Ⅰ)can be used as an optically active identification reagent for aromatic aldehydes,cyclic,aliphatic and aromatic ketones.