摘要
为了寻找具有抑百合鳞茎腐烂病菌活性及抑菌活性的新型化合物。本试验以百合鳞茎腐烂病菌为研究对象,分别采用菌丝生长速率法和盆栽法,测定了倍半萜化合物芳姜黄酮及其衍生物对该病菌的活性。结果表明,芳姜黄酮及其衍生物表现出较好的抑百合鳞茎腐烂病菌活性,尤其是化合物3-甲基-N-(1-(4-氯苯基)乙基)-2-丁烯酰胺和3-甲基-N-(1-(4-甲基苯基)乙基)-2-丁烯酰胺,抑菌率达90%以上,同时这2种化合物在盆栽试验中,防治效果也均达到了84%以上,因此该化合物的结构改造或修饰为创制新型杀菌剂提供了重要依据,具有较好的研究价值。
The purpose of this study was to search for new compounds with antifungal activity and antifungal activity against Lily bulb rot disease.In this study,the activity of ar-turmerone and its derivatives against Lily bulb rot disease was determined by mycelial growth rate method and in vivo pot culture method.The results showed that ar-turmerone and its derivatives exhibited good antibacterial activity against Lily bulb rot disease,especially compounds 3-methyl-N-(1-(4-chlorophenyl)ethyl)-2-butenamide and 3-methyl-N-(1-(4-methylphenyl)ethyl)-2-butenamide,with antibacterial rate of over 90%.At the same time,the control effect of these two compounds in living pot experiments also reached more than 84%,Therefore,the structural modification and modification of these compounds provide an important basis for the creation of new fungicides and have good research value.
作者
胡文杰
殷帅文
戴彩华
周升团
HU Wen-jie*;YIN Shuai-wen;DAI Cai-hua;ZHOU Sheng-tuan(College of Life Science,Jinggangshan University,Ji’an,Jiangxi 343009,China;Faculty of Medicine,Jinggangshan University,Ji’an,Jiangxi 343009,China)
出处
《浙江化工》
CAS
2021年第10期12-16,共5页
Zhejiang Chemical Industry
基金
江西省自然科学基金项目(20181BAB204014)
江西省教育厅科技计划项目(GJJ170641)
国家自然科学基金项目(32160089)。
关键词
油樟
倍半萜成分
有机合成
抑菌活性
构效
Cinnamomum longepaniculatum
sesquiterpenes component
organic synthesis
fungicidal activity
structure-activity relationship