气相色谱法测定痕量铬的多因素试验及在人发分析上应用

Factor Examination on the Gas Chromatographic Determination of Trace Amount Chromium and the Measurement of Chromium in Human Hair

对三氟乙酰丙酮(Htfa)螯合物气相色谱法测铬进行了多因素试验设计;对敏感因素提出了改进措施;找到了消除铝干扰的有效方法,并用改进的方法测定了人发中铬的含量。

The principal conditions of GC determination method for subnanogr-am Cr through Cr (Ⅲ )-trifluoroacetylacetonate were sdudied in detail. A plan of balanced design was selectd for seven factors each with two modified conditions, such that the sensitive factors most likely to influence the results were picked out, improved and emphasized in the procedure. The analytical results for tap water were compared with neutron activation analysis. The coefficient of variation for 1 to 10 ppb Cr in water is ≤3% (n≥6), recovery is in the range of 95-100%, and the 3σ limit of detection is 0.014ppb (n = 22). Four batches of hair samples were analyzed, the Cr content is in the range of 0.42-2.18 μg/g and the coefficient of variation (n = 5) being 10-3% accordingly.