金属有机化合物的分析(Ⅰ)——二茂铁衍生物的薄层色谱分析

ANALYSIS OF ORGANOMETALLIC COMPOUNDS—Ⅰ——THIN-LAYER CHROMATOGRAPHY OF FERROCENE DERIVATIVES

以硅胶为吸附剂,以甲苯:石油醚:丙酮(15:1:1或15:1:3),苯:乙醇(15:1)及甲苯:石油醚:乙醇(15:1:1)为展开剂;分离了二茂铁烃、醚、醛、酮、醇、胺、苯磺酰胺、羧酸及丙烯腈类共42种衍生物,并发现下列规律性:1.化合物结构与比移值之间的关系:(1)随着同类化合物极性逐渐增强,比移值依次递减.(2)随着同一类取代基数目增加,比移值减小,故单取代物>双取代物。2.随着展开剂极性增强,比移值加大。对数种含侧链羟基的二茂铁衍生物所呈现的不符合上述规律的现象,据红外光谱及核磁共振谱作了解释。

Forty-two ferrocene derivatives(including hydrocarbons,ethers,aldehydes,ketones,alcohols,amines,benzenesulfonamides,carboxylic acids,and acrylonitriles)have been separated by thin-layer chroma-tography using silica gel as adsorbent,and toluene-petroleum ether--acetone(15:1:1 or 15:1:3),benzene-alcohol(15:1)or toluene-petroleum ether-alcohol(15:1:1)as development.The following rules have been obtainedⅠ.The relations between the structures of the compounds and their Rs values:1.The Rs values decrease with the increase of the polarity of the substituents of the same series.2.The Rs values decrease with the increase of the number of the substituents of the same type.The Rs values of the monosubsti tuted coinpounds>those of the disubstituted ones.Ⅱ.The Rs values increase with the increase of the polarity of the development.The fact that some ferrocenes derivatives containing side chain hydroxy-group do not obey the rules mentioned above has been explained by means of their IR and NMR spectra.Forty-two ferrocene derivatives(including hydrocarbons,ethers,aldehydes,ketones,alcohols,amines,benzenesulfonamides,carboxylic acids,and acrylonitriles)have been separated by thin-layer chroma-tography using silica gel as adsorbent,and toluene-petroleum ether--acetone(15:1:1 or 15:1:3),benzene-alcohol(15:1)or toluene-petroleum ether-alcohol(15:1:1)as development.The following rules have been obtainedⅠ.The relations between the structures of the compounds and their Rs values:1.The Rs values decrease with the increase of the polarity of the substituents of the same series.2.The Rs values decrease with the increase of the number of the substituents of the same type.The Rs values of the monosubsti tuted coinpounds>those of the disubstituted ones.Ⅱ.The Rs values increase with the increase of the polarity of the development.The fact that some ferrocenes derivatives containing side chain hydroxy-group do not obey the rules mentioned above has been explained by means of their IR and NMR spectra.