醉马草化学成份的研究(Ⅰ)

STUDIES ON THE CHEMICAL COMPOSITIONS OF ACHNATHERUM INEBRIANS

醉马草(Achnatherum inebrians(Hance)Keng)是禾本科芨芨草属植物,分布在我国西北部,是牧场上一种毒草,目前有蔓延趋势。醉马草化学成份及毒理作用,国内外均未曾进行过研究。探明醉马草化学成份对发展畜牧业和医学事业都具有一定意义。

Achnatherum inebrians (Hance) Keng is a toxic grass of pastureland in the Northwest China. Two alkaloids, one neutral substance and one basic composition have been isolated from the plant.By means of MS, NMR, IR, and UV spectra and chemical methods, the two alkaloids are identified as ergonovine (ergometrine) and ergometr-inine respectively. They are isolated for the first time from achnatherum, The principle composition of the neutral substance is 1-octacosanol. Study of the structure of the basic composition, which is possible to be the active principle of the toxic plant, is in progress.