宫颈液基细胞学与人乳头瘤病毒检测在宫颈低级别上皮内病变中的相关性研究

Correlation between cervical liquid based cytology and HPV detection in low-grade cervical intraepithelial lesions

目的:研究宫颈液基细胞学与人乳头瘤病毒(HPV)检测在宫颈低级别上皮内病变中的相关性。方法:选取2015年1月-2017年1月采用宫颈液基细胞学检测联合HPV检测的患者300例,分析检测结果。结果:单一宫颈液基细胞学检测低级别鳞状上皮内病变和高级别上皮内病变分别占0.67%和0.33%;采取宫颈液基细胞学与HPV联合检测低级别鳞状上皮内病变占3.00%、高级别上皮内病变占1.00%。结论:宫颈液基细胞学检测联合HPV检测对宫颈低级别上皮内病变的检测率较高,可有效提高宫颈癌前病变的诊出率,值得临床推广使用。

Objective:To explore the correlation between cervical liquid based cytology and HPV detection in low-grade cervical intraepithelial lesions.Methods:From January 2015 to January 2017,300 patients with cervical liquid-based cytology combined with HPV were selected.We analyzed the test results.Results:The proportions of low-grade squamous intraepithelial lesions and high-grade intraepithelial lesions detected by single cervical liquid-based cytology were 0.67%and 0.33%respectively.The proportion of low-grade squamous intraepithelial lesions detected by cervical liquid-based cytology and HPV was 3.00%,and the proportion of high-grade intraepithelial lesions was 1.00%.Conclusion:Cervical liquid based cytology combined with HPV detection has a high detection rate for low-grade cervical intraepithelial lesions,it can effectively improve the diagnosis rate of cervical precancerous lesions,which is worthy to be popularized in clinic.