吸入用布地奈德混悬液联合异丙托溴铵及硫酸特布他林雾化液用于小儿喘息性支气管炎或支气管肺炎治疗中的作用

The effect of budesonide suspension for inhalation combined with ipratropium bromide and terbutaline sulfate atomized liquid in the treatment of asthmatic bronchitis or bronchopneumonia in children

目的:研究吸入用布地奈德混悬液联合异丙托溴铵及硫酸特布他林雾化液治疗小儿喘息性支气管炎或支气管肺炎的作用。方法:2019年2月-2020年2月收治小儿喘息性支气管炎或支气管肺炎患儿100例,随机分为两组,各50例。对照组给予氨溴特罗口服溶液治疗,观察组在氨溴特罗基础上根据患者病症严重程度给予布地奈德、特布他林及异丙托溴铵联合用药,比较两组治疗效果。结果:观察组治疗总有效率高于对照组,差异有统计学意义(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05);观察组住院时间及各项症状消失时间均低于对照组,差异有统计学意义(P<0.05)。结论:吸入用布地奈德混悬液联合异丙托溴铵及硫酸特布他林雾化液治疗小儿喘息性支气管炎或支气管肺炎效果明显,住院时间更短,且治疗期间不会增加不良反应。

Objective:To study the effect of budesonide suspension for inhalation combined with ipratropium bromide and terbutaline sulfate atomized liquid in the treatment of asthmatic bronchitis or bronchopneumonia in children.Methods:From February 2019 to February 2020,100 children with asthmatic bronchitis or bronchial pneumonia were selected,they were randomly divided into the two groups with 50 cases in each group.The control group was treated with ambroxol oral solution.The observation group was treated with budesonide,terbutaline and ipratropium bromide based on the severity of the patient's condition on the basis of ambroxol.We compared the treatment effects of the two groups.Results:The total effective rate of treatment in the observation group was higher than that in the control group,the difference was statistically significant(P<0.05).The incidence of adverse reactions between the two groups was not statistically significant(P>0.05).The hospitalization time and the disappearance time of various symptoms in the observation group were lower than those in the control group,the difference was statistically significant(P<0.05).Conclusion:Inhalation of budesonide suspension combined with ipratropium bromide and terbutaline sulfate aerosol is effective in the treatment of asthmatic bronchitis or bronchopneumonia in children,with shorter hospital stay and it will not increase adverse reactions during treatment.