摘要
The intracellular delivery of metal-organic frameworks(MOFs)encapsulated with functional biomolecules represents a promising av-enue in the field of biomedicine and biosensing.To improve the cellular uptake efficiency of MOFs,here we report the fabrication of cancer cell-derived exosome membra ne(EM)-coated zeolitic imidazolate framework-8(EM-ZIF-8)nan oparticles by using a microfluidic son ication device.
基金
This work was supported financially by the National Natural Science Foundation of China(Nos.22025402,91959101,and 21904028)
Chinese Academy of Sciences(Nos.YJKYYQ20190068 and ZDBS-LY-SLH025)
the Strategic Priority Research Program of Chinese Academy of Sciences(No.XDB36000000).
