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Design, Synthesis and Biological Evaluation of Novel α-Acyloxycarboxamide-Based Derivatives as c-Met Inhibitors

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摘要 Dysregulated HGF/c-Met signalling has been associated with many human cancers,poor clinical outcomes,and even resistance acquisition to some approved targeted therapies.As such,c-Met kinase has emerged as an attractive target for anticancer drug discovery.
出处 《Chinese Journal of Chemistry》 SCIE CAS CSCD 2021年第8期2241-2250,共10页 中国化学(英文版)
基金 This work was supported by the Fundamental Research Funds for the Central Universities(Nos.31920170193 and 31920200026).
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