加味黄连温胆汤治疗痰火扰心型室性早搏的临床观察

Clinical observation of Modified Huanglian Wendan Decoction in treating ventricular premature beats caused by phlegm and fire

[目的]观察加味黄连温胆汤治疗室性早搏(VPB)的临床疗效。[方法]将80例痰火扰心型VPB患者随机分为两组,每组40例,对照组予以口服琥珀酸美托洛尔缓释片治疗,治疗组同时加用加味黄连温胆汤,疗程为4周,观察并评估两组患者治疗前后VPB发生次数、VPB严重程度分级(Lown分级)、中医症状积分有效率、临床症状改善情况及不良反应发生情况。[结果]治疗后,治疗组疗效、VPB发生次数、Lown分级有效率以及中医症状积分有效率均优于对照组,差异具有统计学意义(P<0.05);两组不良反应总发生率无统计学差异(P>0.05)。[结论]加味黄连温胆汤治疗痰火扰心型VPB临床疗效良好,值得推广应用。

[Objective]To observe the clinical effect of modified huanglian wendan decoction on ventricular premature beats(VPB).[Methods]The 80 patients with phlegm fire disturbance heart-shaped VPB randomly divided into two groups,the 40 cases in each group.The control group was treated by oral Metoprolol,treatment group at the same time combined with Modified Huanglian Wendan Decoction,course of treatment for 4 weeks,observe and assess the occurrence of two groups of patients before and after treatment of VPB occurrences,the grade of VPB severity(Lown hierarchical),traditional Chinese medicine(TCM)syndrome integral,clinical symptoms improved and the occurrence of adverse reactions.[Results]After treatment,the efficacy,VPB occurrences,effective rate of Lown hierarchical and effective rate of TCM syndrome integral in the treatment group were better than those in the control group,with statistical significance(P<0.05).There was no significant difference in the occurrence of adverse reactions between the two groups(P>0.05).[Conclusion]Modified Huanglian Wendan Decoction has a good clinical effect on VPB with phlegm and fire disturbing heart type,which is worthy of popularization and application.