碳苷研究(Ⅵ)——1-芳基-D-吡喃葡萄糖碳苷的快原子轰击质谱

Studies on C-Glycosides(Ⅵ)——Fast-Atom-Bombardment Mass Spectrometry of 1-D-Glucopyranosyl Benzene and Its Derivatives

快原子轰击质谱(FAB-MS)是近几年发展起来的一种质谱新技术,特别适于极性大、不易挥发和对热不稳定的化合物,已用于多肽、核酸及苷的结构测定。 碳苷化合物中含有多羟基,具有极性大、不易挥发的特性,普通的质谱技术为EI或CI,需合成适当的衍生物,才能得到满意的结果,我们应用FAB技术直接测定了4个碳苷化合物的质谱,结果发现这些质谱不但能给出化合物的准确分子量,而且还能够提供有关碳苷化合物结构方面的信息。

Fast-Atom-Bombardment Mass Spectra (FAB-MS) of four 1-D-glucopyranosyl benzene and their derivatives were reported. Accurate molecular weights of the compounds and the rules of cleavage of glucopyranose ring, which had been proved by the FAB-CA-MJKES, were obtained. But, FAB-MS of α,β-isomers of C-glucosides had no obvious differences.