展毛多根乌头的生物碱化学成分研究

Studies on Chemical Ingredients of Aconitum Karakolicum var.Patentipilum

展毛多根乌头(Aconitum karakolicum var.patentipilum W.T.Wang)为毛莨科乌头属植物,是新疆民间常用草药之一,民间称为草乌,主要用于治疗神经痛、牙痛和关节炎等。我们从该植物的根中分离了5个二萜生物碱,用UV、IR、1H NMR、MS等分析结构并与巳知样品的物理数据对照,鉴定为去氧乌头碱(deoxyaconitine)(Ⅰ)。

Five alkaloids have been isolated from the roots of aconitum karakolicum var.patentipilum W.T.Wang,which was collected from Xinjiang province in China.They were identified as deoxyaconitine,songorine,aconitine,neoline and karacoline.All these alkaloids were found first time in this herb.