O-[3-(2′-或4′-吡啶)丙基]硫代磷(膦)酸酯及硫代磷酰胺酯类化合物的研究

Studies on O-s-(2'-OR4'-Pyridyl)Propyl Phosphorothionates,Phosphonothionates and Phosphoroamidothionates

用O,O-二烷基硫代磷酰氯,O-烷基胺基硫代磷酰氯及O-烷基(或芳基)苯基硫代膦酰氯与3-(2′-或4′-吡啶)丙醇缩合制备了相应的硫代磷酸脂,硫代磷酰胺酯共十八个新化合物。测定了它们的红外光谱和核磁共振谱,探索了适宜的反应条件及产物的提纯方法。经初步测试表明某些化合物具有植物激素的活性。

Eighteen new O-3-(2'-or 4'-pyridyl)propyl phosphoronates(Ⅰ),phospho-roamidothionates(Ⅱ)and phosphonothionates(Ⅲ)were prepared by condensing 3-(2'-or 4-pyridyl)propanol with O,O-dialkylphosphorochloridothionates(1)O-alkylphosphoroamidochloridothionates(2)and O-alkyl(or aryl)phenylphos-phonochloridothionates(3),respectively,in presence of a base.The favourable reaction conditions and the purification methods of these compounds were found out.Their 1R and ^(1)HNMR spectra data were given.The results of the primary biological tests showed that some of the compounds enhanced and some inhibited the growth of the coleptiles of wheat.