N,N′-二烷基-氨基甲酰基膦酰胺酯类化合物的合成

Synthesis of Alkyl N,N’-Dialkyl Carbamoyl-phosphonamidates

据Jelinek报道,N,N-二烷基-氨基甲酰基膦酰胺酯类化合物具有抑制植物生长的活性,能影响多种植物的开花和坐果。为探讨这类化合物的合成方法、结构与活性的关系,从而筛选出高效低毒的除草剂,本文合成了通式为RO(R′NH)P(O)C(O)-NHR2的10种新化合物(表1)。对于合成方法进行了初步探讨,其中方法Ⅱ未见文献报道。

Ten new entitled compounds have been prepared and their structures were confirmed. Preliminary bioassays indicated that they have herbicidal and fungicidal activities.