一种新型的含氮冠醚化合物的合成

Synthesis of a New Type Nitrogen-Containing Crown Ether Compounds

本文采用活泼双功能基化合物1,2-双(ω-氯代-多氧杂烷基)-苯〔1,2-双(5-氯-3-氧杂-1-戊氧基)-苯;1,2-双(8-氯-3,6-二氧杂-1-辛氧基)-苯和1,2-双(11-氯-3,6,9-三氧杂-1-10一烷基)-苯〕和N-对甲苯磺酰基取代的多乙撑多胺(二乙撑三胺和三乙撑四胺)二钠盐在无水二甲基甲酰胺中回流反应7—8小时,得到六个新的含氮冠醚化合物(Ⅰ—Ⅵ),收率46—75%。

This paper reports the synthesis of a new nitrogen-containing crown ether compounds (azacrown-ether). Condensation of 1, 2-bis(ω-chloro-polyoxaalkyl)-benzene such as 1, 2-bis (5-chloro-3-oxa-l-pentyloxy)-ben-zene, 1, 2-bis(8-chloro-3, 6-dioxa-l-octyloxy)-benzene and 1,2-bis (11-chloro-3,6,9-trioxa-1-undecyloxy)-benzene with N, N’, N//-tritosyl diethylenetriamine or N, N’, N", N’’ -tetratosyl triethylenetetraamine disodium salts in anhydrous DMF at reflux temperature for 7-8 hours produced six new nitrogen-containing crown ether compounds, yield 46-75%.