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硝苯地平结合硫酸镁对妊娠高血压的降压效果及氧化应激的影响 被引量:2

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摘要 目的:探讨硝苯地平结合硫酸镁治疗妊娠高血压的临床效果。方法:抽取2018年5月至2020年5月福州现代妇产医院收治的68例妊娠高血压患者作为观察对象,按随机数字表法分组,对照组和观察组各34例。对照组用硫酸镁治疗,观察组在对照组基础上叠加应用硝苯地平,观察两组用药前后氧化应激指标,评估临床治疗效果。结果:观察组患者治疗总有效率为91.18%,与对照组的79.41%比较明显更高,差异具有统计学意义(P<0.05)。用药后,观察组患者丙二醛(MDA)水平降低,超氧化物歧化酶(SOD)和谷胱甘肽过氧化物酶(GSH-Px)水平升高,差异具有统计学意义(P<0.05),与对照组比较,观察组MDA更低,SOD、GSH-Px更高,差异具有统计学意义(P<0.05)。结论:硝苯地平结合硫酸镁治疗妊娠高血压可减轻机体氧化应激反应,临床效果确切。
作者 张婕 张方林
出处 《深圳中西医结合杂志》 2021年第16期174-176,共3页 Shenzhen Journal of Integrated Traditional Chinese and Western Medicine
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