自发性卵巢过度刺激综合征合并卵巢破裂一例并文献复习

A Case of Spontaneous Ovarian Hyperstimulation Syndrome with Ovarian Rupture and Literature Review

卵巢过度刺激综合征(ovarian hyperstimulation syndrome,OHSS)是一种医源性疾病,常发生于辅助生殖技术中的控制性超排卵患者,但也可见于自发排卵周期,尤其是多胎妊娠、甲状腺功能减退和多囊卵巢综合征患者,自然妊娠并发OHSS的发生率极低,严重影响患者身体健康,甚至可危及生命。报道1例自发性卵巢过度刺激综合征(spontaneous ovarian hyperstimulation syndrome,sOHSS)并发卵巢破裂的病例,并探讨sOHSS的发病机制、临床表现、并发症、鉴别诊断及治疗,为临床诊治提供参考依据。

Ovarian hyperstimulation syndrome(OHSS)is an iatric disease frequently occurred in patients with controlled ovarian hyperstimulation,but also can be observed in spontaneous ovulation cycles,especially those with multiple-pregnancy,hypothyroidism,polycystic ovary syndrome.The incidence of natural pregnancy complicated with OHSS is very low,which seriously affects the health of patients and even endangers their lives.This paper reported a case of spontaneous ovarian hyperstimulation syndrome(sOHSS)with ovarian rupture,and discussed the pathogenesis,clinical manifestations,complications,differential diagnosis and treatment of sOHSS,so as to provide a reference for clinical treatment.