腹膜透析治疗慢性肾功能衰竭患者的临床效果及对其肾功能指标的影响分析

Clinical effects of peritoneal dialysis in patients with chronic renal failure and its influence on the renal function indicators

目的探讨腹膜透析治疗慢性肾功能衰竭患者的临床效果及对其肾功能指标的影响。方法86例慢性肾功能衰竭患者为研究对象,以随机数字表法将其分为对照组与观察组,各43例。对照组患者予以血液透析治疗,观察组患者予以腹膜透析治疗。比较两组治疗效果、不良事件发生情况、治疗前后生化指标及肾功能指标。结果观察组总有效率为95.35%,高于对照组的90.70%,但差异无统计学意义(P>0.05)。观察组不良事件发生率为4.65%,低于对照组的11.63%,但差异无统计学意义(P>0.05)。治疗后,观察组白蛋白(ALB)为(28.46±3.18)g/L、血红蛋白(Hb)为(94.23±6.58)g/L、红细胞计数(RBC)为(376.54±51.38)×10^(12)/L,均优于对照组的(31.38±2.75)g/L、(86.57±5.43)g/L、(312.35±51.33)×10^(12)/L,差异具有统计学意义(P<0.05)。治疗后,观察组尿素氮(BUN)为(15.33±2.01)mmol/L,低于对照组的(16.42±2.15)mmol/L,差异有统计学意义(P<0.05)。结论在慢性肾功能衰竭患者中实施腹膜透析治疗能有效提升治疗效果,改善患者的肾功能,对提高患者生存质量有积极影响,值得推广。

Objective To discuss the clinical effects of peritoneal dialysis in patients with chronic renal failure and its influence on the renal function indicators.Methods A total of 86 patients with chronic renal failure were selected as the research subjects,and they were divided into control group and observation group according to the random numerical table,with 43 cases in each group.Patients in the control group were treated with hemodialysis,and patients in the observation group were treated with peritoneal dialysis.Both groups were compared in terms of therapeutic effects,occurrence of adverse reactions,biochemical indexes and renal function indexes before and after treatment.Results The total effective rate 95.35%of the observation group was higher than 90.70%of the control group,but the difference was not statistically significant(P>0.05).The incidence of adverse reactions 4.65%in the observation group was lower than 11.63%in the control group,but the difference was not statistically significant(P>0.05).After treatment,the albumin(ALB)(28.46±3.18)g/L,hemoglobin(Hb)(94.23±6.58)g/L,and red blood cell count(RBC)(376.54±51.38)×10^(12)/L of the observation group were better than(31.38±2.75)g/L,(86.57±5.43)g/L and(312.35±51.33)×10^(12)/L of the control group,and the differences were statistically significant(P<0.05).After treatment,the blood urea nitrogen(BUN)(15.33±2.01)mmol/L of the observation group was lower than(16.42±2.15)mmol/L of the control group,and the difference was statistically significant(P<0.05).Conclusion The implementation of peritoneal dialysis in patients with chronic renal failure can effectively enhance the therapeutic effect,improve the renal function of the patients,and have a positive effect on improving the quality of life of the patients.It is worthy of promotion.