美容注射术后皮肤脓肿分枝杆菌感染临床分析

Clinical analysis of Mycobacterium abscessus infection after cosmetic injection

对2018年12月至2019年12月我院确诊的7例皮肤脓肿分枝杆菌感染患者的临床资料进行回顾性分析。本文患者均在非正规医院行美容注射术,术后注射部位都发生脓肿分枝杆菌感染。7例患者均为多发皮损,且为美容注射后发病,表现为红斑、结节、脓肿、溃疡。病理呈感染性肉芽肿改变。6例皮损组织脓液培养结果为脓肿分枝杆菌,1例行组织PCR扩增提示脓肿分枝杆菌感染。诊断为皮肤脓肿分枝杆菌感染。给予克拉霉素、利福平、左氧氟沙星治疗,皮损均消退,随访半年无复发。

The data of 7 patients with Mycobacterium abscessus infection from December 2018 to December 2019 were analyzed retrospectively.All patients underwent cosmetic injections in informal hospitals,and the postoperative injection site was infected with Mycobacterium abscessus.All of the seven patients with mutiple lesions presented with erythema,nodule,abscess and ulceration after cosmetic injection.The biopsy of lesions showed infectious granulomas.The Mycobacterium abscessus was found in the pus of 6 patients and was indentified in skin lesionin one patient through PCR amplification.The diagnosis of Mycobacterium abscess infection was made and the lesions were subside after treated with clarithromycin,rifampicin,levofloxacin,and no recurrence after half a year follow-up.