中西医结合治疗新型冠状病毒肺炎临床观察

Clinical Observation of Integrative Medicine Therapy of COVID-19

目的:观察中西医结合治疗新型冠状病毒肺炎(以下简称新冠肺炎)的临床疗效。方法:采用非随机对照的研究方法,将178例普通型新冠肺炎患者按意愿分为治疗组和对照组,对照组予西医常规治疗,治疗组在对照组治疗基础上联用温阳化湿方及清热宣肺方治疗,比较两组患者临床症状缓解率,淋巴细胞比率恢复情况及病情转归。结果:两组患者发热、咳嗽、乏力、胸闷气短、咽痛、肌肉酸痛等临床症状缓解率治疗组高于对照组,差异具有统计学意义(P<0.05);食欲下降改善两组患者比较差异无统计学意义(P>0.05)。淋巴细胞恢复情况治疗组优于对照组,差异具有统计学意义(P=0.012)。进展为重型、危重型患者对照组多于治疗组,两组比较差异有统计学意义(P=0.034)。结论:西医常规联用温阳化湿方及清热宣肺方能明显缓解新冠肺炎患者临床症状,促进淋巴细胞恢复,降低病情进展风险,但在改善食欲方面无明显优势。

Objective:To assess clinical effects of integrative medicine therapy in the treatment of COVID-19.Methods:Non randomized controlled study was adopted,all 178 patients with common type COVID-19 were allocated to the treatment group and the control group according to the patients'will,the control group accepted conventional theropy ofWestern medicine,and the treatment group took Yang-warming damp-resolving prescription and heat-clearing lung-dispersing prescription based on Western medicine,to compare the remission rate of clinical symptoms,the recovery of lymphocyte ratio and disease outcome between both groups.Results:The remission rate of clinical symptoms including fever,cough,weakness,chest tightness and shortness of breath,sore throat,muscle soreness and others of the treatment group was higher than that of the control group,and the difference had statistical meaning(P<0.05);the difference had no statistical meaning in the improvements of anorexia between both groups(P>0.05).The treatment group was superior to the control group in the recovery of lymphocyte ratio,and the difference showed statistical meaning(P=0.012).The control group was more than the treatment group in the number of developing into severe type and critical type,and the difference showed statistical meaning(P=0.034).Conclusion:Integrative medicine combined with Yang-warming damp-resolving prescription and heat-clearing lung-dispersing prescription could notably improve clinical symptoms of the patients,promote the recovery of lymphocyte and lower the risk of disease progression,while it has no obvious advantage in improving appetite.