三维打印椎间融合器的研究进展

Research progress on three-dimensional printed interbody fusion cage

脊柱融合术是治疗中重度椎间盘疾病的标准术式,近几年三维打印椎间融合器在脊柱融合手术中占据的比重逐步增加。本文综述了三维打印椎间融合器现阶段所采用的成型技术和材料的研究进展,然后依据结构布局,将三维打印椎间融合器归纳为实体-多孔-实体(SPS)型、实体-多孔-框架(SPF)型、框架-多孔-框架(FPF)型、全多孔(WPC)型和其他型等五种类型,并深入分析总结了三维打印椎间融合器的优化发展过程及每种类型椎间融合器的优缺点,后续又介绍并总结了各种类型三维打印椎间融合器的临床应用情况。最后,结合最新研究进展和成果对三维打印椎间融合器在成型技术、应用材料和涂层材料方面的未来研究方向进行了展望,以期为从事椎间融合器研究与应用的学者提供一定的参考。

Spinal fusion is a standard operation for treating moderate and severe intervertebral disc diseases.In recent years,the proportion of three-dimensional printing interbody fusion cage in spinal fusion surgery has gradually increased.In this paper,the research progress of molding technology and materials used in three-dimensional printing interbody fusion cage at present is summarized.Then,according to structure layout,three-dimensional printing interbody fusion cages are classified into five types:solid-porous-solid(SPS)type,solid-porous-frame(SPF)type,frame-porousframe(FPF)type,whole porous cage(WPC)type and others.The optimization process of three-dimensional printing interbody fusion cage and the advantages and disadvantages of each type are analyzed and summarized in depth.The clinical application of various types of 3 D printed interbody fusion cage was introduced and summarized later.Lastly,combined with the latest research progress and achievements,the future research direction of three-dimensional printing interbody fusion cage in molding technology,application materials and coating materials is prospected in order to provide some reference for scholars engaged in interbody fusion cage research and application.